Gene

A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

What are Genes?

Deoxyribonucleic acid (DNA) is the chemical information database that carries the complete set of instructions for the cell as to the nature of the proteins produced by it, its life span, maturity, function and death. Genes are the working subunits of DNA. Each gene contains a particular set of instructions, usually coding for a particular protein or for a particular function.

Gene History

Gene Concepts

Comprehensive cost and utilization of commercial CAR-T therapy in pediatric B-ALL patients

A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, "The price of hope: CAR-T therapy in pediatric leukemia."

17 May 2024

MGH investigators use new drug to save the life of patient with immune thrombotic thrombocytopenic purpura

A team led by investigators from Massachusetts General Hospital, a founding member of the Mass General Brigham healthcare system, used a new drug to save the life of a patient with immune thrombotic thrombocytopenic purpura (iTTP), a rare disorder characterized by uncontrolled clotting throughout the small blood vessels.

17 May 2024

Researchers trace the evolution of key plant protein in lignin synthesis

Scientists from the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have discovered that a protein responsible for the synthesis of a key plant material evolved much earlier than suspected.

17 May 2024

ANU researchers develop new AI tool for rapid, accurate brain tumor classification

A new AI tool to more quickly and accurately classify brain tumors has been developed by researchers at The Australian National University (ANU).

17 May 2024

Johns Hopkins researchers identify key electrical activity behind congenital night blindness

In what they believe is a solution to a 30-year biological mystery, neuroscientists at Johns Hopkins Medicine say they have used genetically engineered mice to address how one mutation in the gene for the light-sensing protein rhodopsin results in congenital stationary night blindness.

17 May 2024

Genetic variants in XDH and SLC2A9 genes linked to T2DM control in Jordanian population

Announcing a new article publication for BIO Integration journal. This study determines the relationships between uric acid levels, specific single nucleotide polymorphisms (SNPs) in genes linked to uric acid metabolism [xanthine dehydrogenase (XDH) and Solute carrier family 2 member 9 (SLC2A9) genes], and control of HbA1c levels in type 2 diabetes mellitus (T2DM) within the Jordanian population.

17 May 2024

New rule of biology highlights benefits of instability in living organisms

A molecular biologist at the USC Dornsife College of Letters, Arts and Sciences may have found a new "rule of biology."

17 May 2024

Novel gene-delivery vehicle shows promise for treating brain disorders

In an important step toward more effective gene therapies for brain diseases, researchers from the Broad Institute of MIT and Harvard have engineered a gene-delivery vehicle that uses a human protein to efficiently cross the blood-brain barrier and deliver a disease-relevant gene to the brain in mice expressing the human protein.

16 May 2024

USC researcher receives $3.1M to study early brain development in babies born to diabetic mothers

It has long been understood that pregnant women with diabetes are more likely to have children with obesity than women who do not have diabetes during pregnancy.

16 May 2024

Genes and age reveal new insights into cognitive variability, study finds

Study examines the effects of specific genes and age on cognition, revealing potential for creating genotype- and cognition-stratified cohorts for future research.

16 May 2024

SMART researchers identify key mechanism behind artemisinin resistance in malaria

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, in collaboration with Massachusetts Institute of Technology (MIT), Columbia University Irving Medical Center (CUIMC), and Nanyang Technological University, Singapore (NTU Singapore), have discovered a link between malaria parasites' ability to develop resistance to antimalarial drugs – specifically artemisinin (ART) – through a cellular process called transfer Ribonucleic acid (tRNA) modification.

16 May 2024

TRPS1 could serve as a new target for drugs against breast cancer

The mammary gland is a complex tissue comprising a variety of cell types. Their proper functioning is crucial for the health of the breast.

16 May 2024

Study demonstrates link between disrupted developmental dopamine signaling and ASD

Recent evidence suggests that dopamine plays a crucial role in neural development. In a novel study, investigators demonstrated the link between disrupted developmental dopamine signaling and autism spectrum disorder (ASD).

16 May 2024

Research expands understanding of vaccine-induced immune thrombocytopenia and thrombosis

New research led by Flinders University and international experts is expanding understanding of vaccine-induced immune thrombocytopenia and thrombosis (known as VITT).

16 May 2024

Repurposing human-approved drugs for prion disease treatment

Prions are the abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins.

16 May 2024

Unveiling the role of neutrophils in lung cancer progression

Lung cancer remains a leading global health concern, responsible for the highest number of cancer-related deaths worldwide.

16 May 2024

Unraveling the mystery of Alzheimer's resilience at molecular level

Everyone experiences aging in their own way, and factors such as genetics, lifestyle and environment play a role in this process.

16 May 2024

Gut microbiota and obesity: New study shows promising results with probiotic and prebiotic intervention

The effect of a low-calorie, sufficient fiber regimen combined with probiotic supplements and physical activity on health, body composition, and physique.

16 May 2024

New study uncovers 17 genes driving clonal hematopoiesis and links to aging and disease

Researchers identified 17 new genes positively selected for clonal hematopoiesis in a large U.K. Biobank cohort, revealing their impact on aging and disease risks.

15 May 2024

COVID-19 linked to rise in autoimmune lung disease, study finds

A study in eBioMedicine identifies shared immunopathology between SARS-CoV-2 infection and MDA5 autoimmunity, highlighting a surge in MDA5+ cases and interstitial lung disease during the COVID-19 pandemic.

15 May 2024

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Gene

Overview

Gene History

Gene Concepts

Latest Gene News and Research

Comprehensive cost and utilization of commercial CAR-T therapy in pediatric B-ALL patients

MGH investigators use new drug to save the life of patient with immune thrombotic thrombocytopenic purpura

Researchers trace the evolution of key plant protein in lignin synthesis

ANU researchers develop new AI tool for rapid, accurate brain tumor classification

Johns Hopkins researchers identify key electrical activity behind congenital night blindness

Genetic variants in XDH and SLC2A9 genes linked to T2DM control in Jordanian population

New rule of biology highlights benefits of instability in living organisms

Novel gene-delivery vehicle shows promise for treating brain disorders

USC researcher receives $3.1M to study early brain development in babies born to diabetic mothers

Genes and age reveal new insights into cognitive variability, study finds

SMART researchers identify key mechanism behind artemisinin resistance in malaria

TRPS1 could serve as a new target for drugs against breast cancer

Study demonstrates link between disrupted developmental dopamine signaling and ASD

Research expands understanding of vaccine-induced immune thrombocytopenia and thrombosis

Repurposing human-approved drugs for prion disease treatment

Unveiling the role of neutrophils in lung cancer progression

Unraveling the mystery of Alzheimer's resilience at molecular level

Gut microbiota and obesity: New study shows promising results with probiotic and prebiotic intervention

New study uncovers 17 genes driving clonal hematopoiesis and links to aging and disease

COVID-19 linked to rise in autoimmune lung disease, study finds

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer